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Saturday, 06 August 2011 03:08

Amides: Health Hazards

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Chemical Name

CAS-Number

ICSC Short-Term Exposure

ICSC Long-Term Exposure

ICSC Routes of Exposure and Symptoms

US NIOSH Target Organs & Routes of Entry

US NIOSH Symptoms

ACETAMIDE       60-35-5

eyes; skin; resp tract

Inhalation: cough, shortness of breath

Skin: redness, pain

Eyes: pain, redness, blurred vision

Ingestion: sore throat, burning sensation

2-ACETYLAMINOFLUORENE     53-96-3

Liver; bladder; kidneys; pancreas; skin; lungs (in animals: tumors of the liver; bladder, pancreas, skin & lungs) Inh, abs, ing, con

Reduced function of liver, kidneys, bladder, pancreas (carc)

ACRYLAMIDE     79-06-1

skin; resp tract; CNS; liver

PNS; CNS

Inhalation: cough, sore throat, weakness

Skin: may be absorbed, redness, pain

Eyes: redness, pain

Ingestion: abdominal pain, weakness

CNS; PNS; skin; eyes, repro sys (in animals: tumors of the lungs, testes, thyroid & adrenal glands) Inh, abs, ing, con

Irrit eyes, skin; ataxia, numb limbs, pares; musc weak; absent deep tendon reflex; hand sweat; ftg, leth; repro effects (carc)

2-CHLOROACETAMIDE    79-07-2

eyes; skin; resp tract; heart; liver; spleen

skin

Inhalation: burning sensation, cough, sore throat

Skin: redness, pain

Eyes: redness, pain

Ingestion: sore throat

CYCLOPHOSPHAMIDE    50-18-0

eyes; skin; resp tract; kidneys; bladder; CVS; CNS; GI tract; liver; heart; blood

skin

Inhalation: diarrhoea, dizziness, loss of hair, darkening of skin and finger nails, nausea, vomiting

Skin: may be absorbed

DIMETHYL ACETAMIDE     127-19-5

eyes; skin; resp tract

skin; liver; kidneys

Inhalation: headache, nausea, vomiting

Skin: may be absorbed, redness

Eyes: Vapour will be absorbed, redness, pain

CNS; liver; skin Inh, abs, ing, con

irrit skin; jaun, liver damage; depres, leth, halu, delusions

DIMETHYLFORMAMIDE    68-12-2

eyes; skin; resp tract; liver; CNS

liver

Inhalation: loss of appetite, abdominal pain, diarrhoea, dizziness, nausea, vomiting, nervous agitation, facial flushing and alcohol intolerance

Skin: may be absorbed, dry skin, redness, roughness

Eyes: redness, pain

Eyes; liver; kidneys; CVS; skin; resp sys Inh, abs, ing, con

Irrit eyes, skin, resp sys; nau, vomit, colic; liver damage, enlarged liver; high BP; face flush; derm; in animals: kidney, heart damage

FORMAMIDE      75-12-7

lungs; CNS

liver

Inhalation: drowsiness, headache, nausea, unconsciousness

Skin: may be absorbed, redness

Eyes: redness

Ingestion: abdominal pain

Eyes; skin; resp sys; CNS; repro sys Inh, ing, con

Irrit eyes, skin, muc memb; drow, ftg; nau, acidosis; skin eruptions; in animals: repro effects

 

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Read 2829 times Last modified on Friday, 09 December 2011 20:08

Contents

Preface
Part I. The Body
Part II. Health Care
Part III. Management & Policy
Part IV. Tools and Approaches
Part V. Psychosocial and Organizational Factors
Part VI. General Hazards
Part VII. The Environment
Part VIII. Accidents and Safety Management
Part IX. Chemicals
Part X. Industries Based on Biological Resources
Part XI. Industries Based on Natural Resources
Part XII. Chemical Industries
Part XIII. Manufacturing Industries
Part XIV. Textile and Apparel Industries
Part XV. Transport Industries
Part XVI. Construction
Part XVII. Services and Trade
Part XVIII. Guides