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Saturday, 06 August 2011 03:31

Aromatic Amino Compounds: Health Hazards

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Chemical Name

CAS-Number

ICSC Short-Term Exposure

ICSC Long-Term Exposure

ICSC Routes of Exposure and Symptoms

US NIOSH Target Organs & Routes of Entry

US NIOSH Symptoms

4-AMINODIPHENYL         92-67-1

eyes; bladder

Inhalation: dullness, headache

Skin: may be absorbed

Eyes: redness

Bladder; skin (bladder cancer)Inh; abs; ing; con

Head, dizz; leth, dysp; ataxia, weak; methemo; urinary burning; acute hemorrhagic cystitis; (carc)

o-AMINOPHENOL            95-55-6

blood

skin

Inhalation: blue lips or finger nails, blue skin, cough, dizziness, headache, laboured breathing, unconsciousness, symptoms may be delayed

Eyes: Redness

ANILINE            62-53-3

eyes; blood; CNS

liver; kidneys; spleen; skin; blood

Inhalation: blue lips or finger nails, blue skin, headache, dizziness, laboured breathing, convulsions, increased heartbeat, vomiting, weakness, unconsciousness

Skin: may be absorbed

Eyes: redness

Blood; CVS; eyes; liver; kidneys; resp sys  (in animals: tumors of the spleen) Inh; abs; ing; con

Head, weak, dizz; cyan; ataxia; dysp on effort; tacar; irrit eyes; methemo; cirr; (carc)

ANILINE HYDROCHLORIDE     142-04-1

eyes; skin; resp tract; blood

skin; spleen; kidneys; blood

Inhalation: blue lips or finger nails, blue skin, cough, dizziness, headache, nausea, shortness of breath, sore throat, unconsciousness, vomiting, weakness

Skin: may be absorbed, redness

Eyes: redness, pain

Ingestion: abdominal pain

o-ANISIDINE      90-04-0

blood

blood

Inhalation: blue lips or finger nails, blue skin, dizziness, drowsiness, headache, nausea, vomiting

Skin: may be absorbed

Blood; kidneys; liver; CVS; CNSInh; abs; ing; con

Head, dizz; cyan; RBC Heinz bodies; (carc)

p-ANISIDINE      104-94-9

blood

blood

Inhalation: blue lips or finger nails, blue skin, dizziness, drowsiness, headache, laboured breathing, nausea, vomiting

Skin: may be absorbed, blue lips or fingernails, blue skin

Ingestion: blue lips or fingernails, blue skin

Blood; kidneys; liver; CVS; CNSInh; abs; ing; con

Head, dizz; cyan; RBC Heinz bodies; (carc)

BENZIDINE        92-87-5

Bladder; kidneys; liver; skin; blood  (liver, kidney and bladder cancer) Inh; abs; ing; con

Hema; secondary anemia from hemolysis; acute cystitis; acute liver disorders; derm;  painful, irreg urination; (carc)

o-CHLOROANILINE         95-51-2

eyes; skin

skin; liver; kidneys; blood

Inhalation: blue lips or finger nails, blue skin, convulsions, diarrhoea, dizziness, headache, nausea, shortness of breath, vomiting, weakness

Skin: may be absorbed, redness

Eyes: redness, pain

Ingestion: abdominal pain

m-CHLOROANILINE         108-42-9

eyes; skin; resp tract; liver; kidneys

blood

Inhalation: blue lips or finger nails, blue skin, dizziness, drowsiness, headache, nausea, shortness of breath, unconsciousness

Skin: may be absorbed, redness, burning sensation

Eyes: redness, pain, severe deep burns

Ingestion: abdominal pain,

p-CHLOROANILINE         106-47-8

eyes; skin; resp tract; blood

skin ; blood; liver; kidneys; spleen ; bone marrow

Inhalation: blue lips or finger nails, blue skin, dizziness, headache, laboured breathing

Skin: may be absorbed, redness

Eyes: redness, pain

Ingestion: nausea

2,4-DIAMINOTOLUENE    95-80-7

eyes; skin; resp tract; lungs; heart; liver; blood

skin

Inhalation: blue lips or finger nails, blue skin, dizziness, increased heart rate, laboured breathing, nausea, vomiting, convulsions, respiratory depression

Skin: may be absorbed, redness on contact with molten material - skin burns, blisters

Eyes: redness

Ingestion: abdominal pain, blue skin, headache, nausea, vomiting

Eyes, skin, resp sys, blood, CVS, liver, CNS  (in animals: liver, skin & mammary gland tumors) Inh; abs; ing; con

Irrit eyes, skin, nose, throat; derm; ataxia, tacar, nau, vomit, convuls, resp depres; methemo, cyan, head, ftg, dizz, bluish skin; liver inj; (carc)

2,6-DIAMINOTOLUENE    823-40-5

eyes; skin; resp tract; blood

skin

Inhalation: blue lips or finger nails, blue skin, cough, dizziness, headache, shortness of breath

Skin: redness

Eyes: redness, pain

Ingestion: laboured breathing

2,3-DICHLOROANILINE    608-27-5

liver; kidneys

skin ; blood

Inhalation: blue lips or finger nails, blue skin, convulsions, diarrhoea, dizziness, headache, shortness of breath, vomiting, weakness

Skin: may be absorbed, redness

Eyes: redness, pain

2,4-DICHLOROANILINE    554-00-7

liver; kidneys

skin ; blood

Inhalation: blue skin, dizziness, headache, shortness of breath

Skin: may be absorbed, redness, skin burns

Eyes: redness, pain, severe deep burns

Ingestion: abdominal pain, nausea

2,5-DICHLOROANILINE    95-82-9

liver; kidneys

skin ; blood

Inhalation: blue skin, dizziness, headache, shortness of breath

Skin: may be absorbed, redness, skin burns

Eyes: redness, pain, severe deep burns

Ingestion: abdominal pain, nausea

2,6-DICHLOROANILINE    608-31-1

liver; kidneys

skin ; blood

Inhalation: blue skin, dizziness, headache, shortness of breath

Skin: may be absorbed, redness

Eyes: redness, pain

3,4-DICHLOROANILINE    95-76-1

liver; kidneys

skin; blood

Inhalation: blue skin, dizziness, headache, shortness of breath

Skin: may be absorbed, redness, burning sensation

Eyes: redness, pain, severe deep burns

Ingestion: abdominal pain, nausea

3,3'-DICHLOROBENZIDINE     91-94-1

resp tract

skin; liver

Inhalation: cough, sore throat

Skin: may be absorbed

Bladder; liver; lung ; skin; GI tract  (in animals: liver & bladder cancer) Inh; abs; ing; con

Skin sens, derm; head, dizz; caustic burns; frequent urination, dysuria; hema; GI upset; upper resp infection; (carc)

DIMETHYLANILINE          121-69-7

blood

skin

Inhalation: abdominal pain, blue skin, dizziness, headache, ringing in the ears, laboured breathing, unconsciousness, vomiting, visual disturbance

Skin: may be absorbed, redness

Eyes: redness, pain

Blood; kidneys;liver; CVSInh; abs; ing; con

Anoxia US NIOSH Symptoms; cyan, weak, dizz, ataxia; methemo

DIMETHYLAMINOAZOBENZENE     60-11-7

Skin; resp sys; liver; kidneys; bladder ( in animals: liver & bladder tumors) Inh; abs; ing; con

Enlarged liver; liver, kidney dysfunc; contact derm; cough, wheez, dysp; bloody sputum; bronchial secretions; frequent urination, hema, dysuria; (carc)

N,N-DIMETHYL-p-TOLUIDINE     99-97-8

blood; brain; kidneys

Inhalation: blue lips or finger nails, blue skin, dizziness, headache, shortness of breath, weakness

Skin: may be absorbed

2,4-DINITROANILINE       97-02-9

eyes; skin; resp tract; blood

blood

Inhalation: blue lips or finger nails, blue skin, cough, dizziness, headache, laboured breathing, nausea, sore throat

Skin: may be absorbed, redness, blue lips or fingernails, blue skin

Eyes: redness, pain

Ingestion: unconsciousness

DIPHENYLAMINE            122-39-4

eyes; skin; resp tract

kidneys

Inhalation: cough, sore throat

Skin: redness

Eyes: redness

Eyes; skin; resp sys; CVS; blood; bladder; repro sysInh; abs; ing; con

Irrit eyes, skin muc memb; eczema; tacar, hypertension; cough, sneez; methemo; incr BP, heart rate; prot, hema, bladder inj; in animals: terato effects

N-ISOPROPYLANILINE    768-52-5

skin; blood; brain; kidneys

skin ; blood

Inhalation: blue lips or finger nails, blue skin, dizziness, headache, laboured breathing

Skin: may be absorbed, blue lips or fingernails, blue skin

Eyes: redness, pain, blurred vision

Ingestion: nausea

Eyes; skin; resp sys; blood; CVS; liver; kidneysInh; abs; ing; con

Irrit eyes, skin; head, weak, dizz; cyan; ataxia; dysp on effort; tacar; methemo

N-ISOPROPYL-N'-PHENYL-p-¬≠PHENYLENEDIAMINE      101-72-4

eyes; skin

skin

Inhalation: cough, irritant

Skin: redness, irritant

Eyes: redness, irritant

METHYLANILINE 100-61-8

eyes; skin; resp tract; blood; brain; kidneys

skin; blood

Inhalation: blue lips or finger nails, blue skin, cough, dizziness, headache, laboured breathing, sore throat

Skin: may be absorbed, redness, pain

Eyes: redness, pain, blurred vision

Ingestion: abdominal pain, blue lips or fingernails, blue skin, dizziness, headache, laboured breathing, nausea

Resp sys; liver; kidneys; blood; CNSInh; abs; ing; con

Weak, dizz, head; dysp, cyan; methemo; pulm edema; liver, kidney damage

1,5-NAPHTHALENEDIAMINE     2243-62-1

skin

Skin: may be absorbed

a-NAPHTHYLAMINE        134-32-7

Bladder; skin  (bladder cancer) Inh; abs; ing; con

Derm; hemorrhagic cystitis; dysp, ataxia, methemo; hema; dysuria; (carc)

b-NAPHTHYLAMINE         91-59-8

Bladder; skin  (bladder cancer) Inh; abs; ing; con

Derm; hemorrhagic cystitis; dysp; ataxia; methemo, hema; dysuria; (carc)

o-NITROANILINE 88-74-4

blood

Inhalation: blue lips or finger nails, blue skin, dizziness, drowsiness, headache, laboured breathing, nausea, shortness of breath, unconsciousness, weakness

Skin: may be absorbed, blue lips or fingernails, blue skin

m-NITROANILINE            99-09-2

blood

Inhalation: blue lips or finger nails, blue skin, dizziness, drowsiness, headache, laboured breathing, nausea, shortness of breath, unconsciousness, weakness

Skin: may be absorbed, blue lips or fingernails, blue skin

p-NITROANILINE 100-01-6

blood

liver

Inhalation: blue lips or finger nails, blue skin, dizziness, drowsiness, headache, laboured breathing, nausea, shortness of breath, unconsciousness, weakness

Skin: may be absorbed, blue lips or fingernails, blue skin

Resp sys; blood; heart; liver; ­abs; ing; con

Irrit nose, throat; cyan, ataxia; tacar, tachypnea; dysp; irrity; vomit, diarr; convuls; resp arrest; anemia; methemo; jaundice

N-PHENYL-1-NAPHTHYLAMINE     90-30-2

skin

Skin: redness

p-PHENYLENEDIAMINE   106-50-3

resp tract; blood; kidneys

skin; resp tract

Inhalation: cough, dizziness, headache, laboured breathing

Skin: redness

Eyes: redness, blurred vision, even permanent loss of vision

Ingestion: abdominal pain, blue lips or fingernails, blue skin, vomiting, weakness, convulsions, coma, death

Resp sys ; skinInh; abs; ing; con

Irrit pharynx, larynx; bronchial asthma; sens derm

p-PHENYLENEDIAMINE HYDROCHLORIDE           624-18-0

eyes; skin; resp tract; blood; brain; kidneys

skin; resp tract; liver

Inhalation: cough, dizziness, laboured breathing, see ingestion

Skin: redness

Eyes: blurred vision, even permanent loss of vision

Ingestion: abdominal pain, blue lips or fingernails, blue skin, vomiting, weakness, swelling of the face and neck, convulsions, coma, death

o-TOLIDINE        119-93-7

eyes; skin; resp tract

skin; blood

Inhalation: cough, weak irritant

Skin: may be absorbed

Eyes; resp sys; liver; kidneys; (in animals: liver, bladder & mammary gland tumors)Inh; abs; ing; con

Irrit eyes, nose; in animals: liver, kidney damage; (carc)

o-TOLUIDINE      95-53-4

Eyes; skin; blood; kidneys; liver; CVS  (in animals: liver, bladder & mammary gland tumors) Inh; abs; ing; con

Irrit eyes; anoxia, head, cyan; weak, dizz, drow; micro hema, eye burns; derm;  (carc)

XYLIDINE          1300-73-8

eyes; skin; resp tract; blood

kidneys; liver; red blood cells

Inhalation: blue lips or finger nails, blue skin, dizziness, headache, laboured breathing

Skin: may be absorbed

Eyes: redness, pain, blurred vision

Ingestion: blue lips or fingernails, blue skin, dizziness, headache

Resp sys; blood; liver; kidneys; CVSInh; abs; ing; con

Anoxia, cyan, methemo; lung, liver, kidney damage

 

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Read 2947 times Last modified on Friday, 09 December 2011 20:01

Contents

Preface
Part I. The Body
Part II. Health Care
Part III. Management & Policy
Part IV. Tools and Approaches
Part V. Psychosocial and Organizational Factors
Part VI. General Hazards
Part VII. The Environment
Part VIII. Accidents and Safety Management
Part IX. Chemicals
Part X. Industries Based on Biological Resources
Part XI. Industries Based on Natural Resources
Part XII. Chemical Industries
Part XIII. Manufacturing Industries
Part XIV. Textile and Apparel Industries
Part XV. Transport Industries
Part XVI. Construction
Part XVII. Services and Trade
Part XVIII. Guides