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Sunday, 07 August 2011 06:37

Heterocyclic Compounds: Health Hazards

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Chemical Name

CAS-Number

ICSC Short-Term Exposure

ICSC Long-Term Exposure

ICSC Routes of Exposure and Symptoms

US NIOSH Target Organs & Routes of Entry

US NIOSH Symptoms

2-AMINOPYRIDINE          504-29-0

Inhalation: convulsions, dizziness, headache, nausea, shortness of breath, weakness, increased blood pressure, collapse

CNS; resp sys Inh; abs; ing; con

Irrit eyes, nose, throat; head, dizz, excitement; nau; high BP; resp distress; weak; convuls; stupor

3,6-DICHLOROPICOLINIC ACID     1702-17-6

eyes; resp tract

liver; kidneys

Inhalation: cough, dullness

2-MERCAPTOBENZOTHIAZOLE     149-30-4

eyes

skin

Inhalation: cough

Skin: redness

Eyes: redness, pain

2-MERCAPTOBENZOTHIAZOLE DISULPHIDE      120-78-5

eyes; skin; resp tract

skin

Inhalation: cough, sore throat

Skin: may be absorbed, redness

Eyes: redness

2-METHYLPYRIDINE        109-06-8

eyes; skin; resp tract

skin; CNS

Inhalation: burning sensation, cough, dizziness, drowsiness, headache, laboured breathing, nausea, sore throat, unconsciousness, weakness

Skin: may be absorbed, dry skin, redness, burning sensation, pain, blisters

Eyes: pain, blurred vision, severe deep burns

Ingestion: abdominal pain, burning sensation, diarrhoea, vomiting

3-METHYLPYRIDINE        108-99-6

eyes; skin; resp tract

skin; CNS

Inhalation: burning sensation, cough, dizziness, drowsiness, headache, laboured breathing, nausea, sore throat, unconsciousness, weakness

Skin: may be absorbed, dry skin, redness, burning sensation, pain, blisters

Eyes: pain, blurred vision, severe deep burns

Ingestion: abdominal pain, burning sensation, diarrhoea, vomiting

4-METHYLPYRIDINE        108-89-4

eyes; skin; resp tract

skin; CNS

Inhalation: burning sensation, cough, dizziness, drowsiness, headache, laboured breathing, nausea, sore throat, unconsciousness, weakness

Skin: may be absorbed, dry skin, redness, burning sensation, pain, blisters

Eyes: pain, blurred vision, severe deep burns

Ingestion: abdominal pain, burning sensation, diarrhoea, vomiting

1-METHYL-2-PYRROLIDONE     872-50-4

resp tract; eyes

lungs; bone marrow; lymphatic system

Inhalation: cough, laboured breathing

Skin: may be absorbed

Eyes: redness, pain, blurred vision, loss of vision; abdominal cramps, diarrhoea, laboured breathing

MORPHOLINE    110-91-8

eyes; skin; resp tract; lungs

liver; kidneys

Inhalation: Ingestion: burning sensation, cough, laboured breathing, shortness of breath, sore throat

Skin: may be absorbed, redness, skin burns, pain

Eyes: redness, pain, blurred vision

Ingestion: abdominal pain, cough, diarrhoea, vomiting

Resp sys; eyes; skin; liver; kidneys Inh; abs; ing; con

Irrit eyes, skin, nose, resp sys; vis dist; cough; in animals: liver, kidney damage

NICOTINE          54-11-5

Inhalation: abdominal pain, headache, nausea, vomiting, tremors, convulsions,

CNS; CVS; lungs; GI tract; repro sys Inh; abs; ing; con

Nau, salv, abdom pain, vomit, diarr; head, dizz, hearing, vis dist; conf, weak, inco; paroxysmal atrial fibrl; convuls, dysp; in animals: terato effects

NICOTINE TARTRATE      65-31-6

eyes; skin; CNS

Inhalation: abdominal pain, headache, nausea, vomiting, tremors, convulsions

Skin: may be absorbed

Eyes: redness, pain

PHENOTHIAZINE            92-84-2

eyes; skin; resp tract; blood; liver

skin

Inhalation: cough, sore throat

Skin: may be absorbed, redness, pain, itching, coloured yellow-brown skin

Eyes: redness, pain, blurred vision

Skin; CVS; liver; kidneys Inh; abs; ing; con

Itching, irrit, reddening skin; hepatitis, hemolytic anemia, abdom cramps, tacar; kidney damage; skin photo sens

PHENYLENEPYRENE      193-39-5

Skin: may be absorbed

PIPERIDINE       110-89-4

Inhalation: burning sensation, cough, laboured breathing

PROPYLENE IMINE         75-55-8

eyes; skin; resp tract; lungs ; CNS

skin

Inhalation: cough, dizziness, headache, laboured breathing, shortness of breath, unconsciousness

Skin: may be absorbed, redness, skin burns, itching, blisters

Eyes: redness, pain, blurred vision

Ingestion: burning sensation of the digestive tract, dizziness, headache, nausea, vomiting

Eyes; skin (in animals: nasal tumors) Inh; abs; ing; con

Eye, skin burns; (carc)

PYRIDINE          110-86-1

eyes; skin; resp tract; GI tract; CNS; CVS

skin; liver; kidneys

Inhalation: cough, dizziness, headache, nausea, shortness of breath, unconsciousness

Skin: may be absorbed, redness

Eyes: redness, pain

Ingestion: abdominal pain, diarrhoea, vomiting, weakness

Eyes; skin; CNS; liver; kidneys; GI tract Inh; abs; ing; con

Irrit eyes; head, ner, dizz, insom; nau, anor, derm; liver, kidney damage

2-PYRROLIDINONE         616-45-5

eyes

QUINOLINE        91-22-5

eyes; resp tract; CNS

liver; kidneys; retina

Inhalation: cough, laboured breathing, nausea, shortness of breath, vomiting, weakness

Skin: may be absorbed, redness, skin burns

Eyes: redness, pain, blurred vision

TETRAHYDROTHIOPHENE     110-01-0

eyes; skin; resp tract; CNS

skin

Inhalation: Burning sensation, cough, headache, sore throat

Skin: may be absorbed, dry skin, redness, burning sensation

Eyes: redness, pain, eyes

Ingestion: abdominal pain

THIOPHENE       110-02-1

eyes; skin; resp tract

Inhalation: cough, sore throat

Skin: may be absorbed

Eyes: redness, pain

 

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Read 3094 times Last modified on Friday, 09 December 2011 19:28

Contents

Preface
Part I. The Body
Part II. Health Care
Part III. Management & Policy
Part IV. Tools and Approaches
Part V. Psychosocial and Organizational Factors
Part VI. General Hazards
Part VII. The Environment
Part VIII. Accidents and Safety Management
Part IX. Chemicals
Part X. Industries Based on Biological Resources
Part XI. Industries Based on Natural Resources
Part XII. Chemical Industries
Part XIII. Manufacturing Industries
Part XIV. Textile and Apparel Industries
Part XV. Transport Industries
Part XVI. Construction
Part XVII. Services and Trade
Part XVIII. Guides