Friday, 05 August 2011 00:05

Acids and Anhydrides,Organic: Health Hazards

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Chemical Name

CAS-Number

ICSC Short-Term Exposure

ICSC Long-Term Exposure

ICSC Routes of Exposure and Symptoms

US NIOSH Target Organs & Routes of Entry

US NIOSH Symptoms

ACETIC ACID     64-19-7

eyes; skin; resp tract; lungs

skin

Inhalation: sore throat, cough, shortness of breath, laboured breathing, symptoms may be delayed

Skin: redness, serious skin burns, pain

Eyes: pain, redness, blurred vision, severe deep burns

Ingestion: abdominal pain, burning sensation, diarrhoea, sore throat, vomiting

Resp sys; skin; eyes; teeth Inh; con

Irrit eyes, nose, throat; eye, skin burns; derm; conj; cough; CNS depres; delayed pulm edema; in animals: kidney, repro, terato effects

ACETIC ANHYDRIDE       108-24-7

eyes; skin; resp tract

skin

Inhalation: corrosive, cough, laboured breathing, shortness of breath, sore throat, symptoms may be delayed

Skin: corrosive, redness, pain, blisters

Eyes: corrosive, redness, pain, severe deep burns

Ingestion: corrosive, abdominal pain, sore throat, collapse

Resp sys; skin; eyes Inh; con

Conj, lac, corn edema, opac, photo; nasal, phar irrit; cough, dysp, bron; skin burns, vesic, sens derm

ACETYLSALICYLIC ACID 50-78-2

eyes; skin; resp tract

liver; kidneys; bladder; GI tract; CVS; CNS; resp tract

Inhalation: cough, dullness

Skin: redness

Eyes: redness

Eyes; skin; resp sys; blood; liver; kidney Inh; ing; con

Irrit eyes, skin, upper resp sys; incr blood clotting time; nau, vomit; liver, kidney inj

ACRYLIC ACID   79-10-7

eyes; skin; resp tract; lungs

Inhalation: burning sensation, cough, nasal discharge, laboured breathing, sore throat

Skin: may be absorbed, redness, pain, blisters

Eyes: redness, pain, loss of vision, severe deep burns

Ingestion: severe burns to lips, mouth and throat, abdominal cramps, diarrhoea, unconsciousness, shock

Eyes, skin, resp sys Inh; abs; ing; con

Irrit eyes, skin, resp sys; eye, skin burns; skin sens; in animals: lung, liver, kidney inj

ADIPIC ACID      124-04-9

eyes; skin; resp tract

skin

Inhalation: cough, laboured breathing, sore throat

Skin: redness

Eyes: redness, pain

L-ASCORBIC ACID          50-81-7

eyes; resp tract

Inhalation: cough

Eyes: redness

Ingestion: only in case of large amount ingested: diarrhoea, vomiting

BENZOIC ACID   65-85-0

eyes; skin; resp tract

skin

Inhalation: cough, irritant

Skin: redness, irritant

Eyes: redness, irritant, pain

Ingestion: abdominal pain, nausea, vomiting

n-CAPROIC ACID            142-62-1

eyes; skin; resp tract

skin

Inhalation: cough, sore throat

Skin: may be absorbed, redness, burning sensation, pain

Eyes: redness, pain, blurred vision

Ingestion: abdominal pain, nausea, sore throat, vomiting

CHLOROACETIC ACID     79-11-8

Inhalation: corrosive, burning sensation, cough, laboured breathing, sore throat, symptoms may be delayed

Skin: corrosive, may be absorbed, redness, pain, blisters

Eyes: redness, pain, severe deep burns

Ingestion: abdominal cramps, burning sensation, collapse

CITRIC ACID      77-92-9

eyes; skin; resp tract

Inhalation: burning sensation, cough, laboured breathing

Skin: redness

Eyes: redness, pain

Ingestion: cough

CITRIC ACID HYDRATE     5949-29-1

eyes; resp tract

Inhalation: cough, sore throat

Skin: redness

Eyes: redness, pain

Ingestion: sore throat, mild burning sensation

CROTONIC ACID 3724-65-0

eyes; skin; resp tract; lungs

skin

Inhalation: burning sensation, cough, headache, nausea, shortness of breath, sore throat, symptoms may be delayed

Skin: skin burns, burning sensation, pain

Eyes: pain, blurred vision, severe deep burns

Ingestion: pain, burning sensation, diarrhoea, sore throat, vomiting

DICHLOROACETIC ACID  79-43-6

eyes; skin; resp tract; lungs

Inhalation: burning sensation, cough, laboured breathing, unconsciousness, symptoms may be delayed

Skin: redness, pain, blisters

Eyes: redness, pain, severe deep burns

Ingestion: abdominal cramps, burning sensation, sore throat, unconsciousness, vomiting, weakness

2,4-DICHLOROPHENOXYACETIC ACID     94-75-7

eyes; skin; resp tract

Inhalation: headache, nausea, weakness

Skin: redness

Eyes: redness

Ingestion: abdominal pain, burning sensation, diarrhoea, headache, nausea, unconsciousness, vomiting, weakness

Skin; CNS; liver; kidneys Inh; abs; ing; con

Weak, stupor, hyporeflexia, musc twitch; convuls; derm; in animals: liver, kidney inj

ETHANEDIOIC ACID, DIHYDRATE       6153-56-6

eyes; skin; resp tract; lungs; kidneys

kidneys

Inhalation: cough, shortness of breath, sore throat

Skin: may be absorbed, dry skin, redness, skin burns, pain, blisters

Eyes: redness, pain, severe deep burns

Ingestion: abdominal cramps, sore throat, vomiting, weakness, convulsions

2-ETHYLHEXANOIC ACID 149-57-5

eyes; skin; resp tract

liver

Skin: rednessEyes: redness, pain

FLUOROACETIC ACID     144-49-0

eyes; skin; resp tract; CVS; CNS; kidneys

FORMIC ACID     64-18-6

eyes; skin; resp tract; lungs

skin

Inhalation: burning sensation, cough, laboured breathing, shortness of breath, symptoms may be delayed

Skin: redness, serious skin burns, pain

Eyes: redness, pain, blurred vision, severe deep burns

Ingestion: abdominal pain, burning sensation, diarrhoea, sore throat, vomiting

Eyes; skin; resp sys Inh; ing; con

Irrit eyes, skin, throat; skin burns; derm; lac; rhin; cough, dysp; nau

LACTIC ACID      598-82-3

eyes; skin; resp tract

Inhalation: cough, shortness of breath, sore throat, symptoms may be delayed

Skin: redness, skin burns, pain

Eyes: redness, pain, severe deep burns

Ingestion: abdominal pain, burning sensation, nausea, sore throat, vomiting

MALEIC ACID     110-16-7

eyes; skin; resp tract

skin; kidneys

Inhalation: cough, laboured breathing

Skin: redness, skin burns, severe irritant

Eyes: redness, pain, blurred vision

Ingestion: burning sensation, see inhalation ,

MALEIC ANHYDRIDE       108-31-6

eyes; skin; resp tract

skin

Inhalation: cough, headache, laboured breathing, nausea, shortness of breath, vomiting

Skin: redness, skin burns

Eyes: redness, pain, lacrymation, severe deep burns

Ingestion: abdominal pain

Eyes; skin; resp sys Inh; ing; con

Irrit nose, upper resp sys; conj; photo, double vision; bronchial asthma; derm

METHACRYLIC ACID       79-41-4

eyes; skin; mucous membranes; resp tract; lungs

Inhalation: burning sensation, cough, laboured breathing

Skin: redness, skin burns, pain, blisters

Eyes: redness, pain, loss of vision, severe deep burns

Ingestion: abdominal cramps, abdominal pain, burning sensation, weakness

Eyes; skin; resp sys Inh; abs; ing; con

Irrit eyes, skin, muc memb; eye, skin burns

2-METHYL-4-CHLOROPHENO­ACETIC ACID     94-74-6

eyes; skin; resp tract

birth defects

Inhalation: headache, nausea

Skin: redness

Eyes: redness

Ingestion: abdominal pain, nausea, unconsciousness, vomiting, weakness

OXALIC ACID     144-62-7

eyes; skin; resp tract; lungs; kidneys

skin; kidneys

Inhalation: burning sensation, cough, laboured breathing, sore throat, symptoms may be delayed

Skin: redness, skin burns, pain, blisters

Eyes: redness, pain, blurred vision, loss of vision, severe deep burns

Ingestion: burning sensation, drowsiness, sore throat, vomiting, shock, low back pain

Resp sys; skin; kidneys; eyes Inh; ing; con

Irrit eyes, skin, muc memb; eye burns; local pain, cyan; shock, collapse, convuls; kidney damage

PALMITIC ACID  57-10-3

eyes; skin; resp tract; lungs

skin

Eyes: redness

PHTHALIC ANHYDRIDE    85-44-9

eyes; skin; resp tract

skin; lungs

Resp sys; eyes; skin; liver; kidneys Inh; ing; con

Irrit eyes, skin, upper resp sys; conj; nasal ulcer bleeding; bron, bronchial asthma; derm; in animals: liver, kidney damage

PHTHALIC ACID  88-99-3

eyes; skin; resp tract

Inhalation: cough

Skin: redness

Eyes: redness, pain

PROPIONIC ACID           79-09-4

eyes; skin; resp tract

Inhalation: cough, laboured breathing, sore throat

Skin: skin burns, pain, blisters

Eyes: redness, pain, blurred vision, severe deep burns

Ingestion: abdominal pain, nausea, sore throat, vomiting,

Eyes; skin; resp sys Inh; abs; ing; con

Irrit eyes, skin, nose, throat; blurred vision, com burns; skin burns; abdom pain, nau, vomit

PROPIONIC ANHYDRIDE 123-62-6

eyes; skin; resp tract; lungs

Inhalation: burning sensation, cough, laboured breathing, sore throat, symptoms may be delayed

Skin: redness, skin burns

Eyes: redness, severe deep burns

Ingestion: sore throat, burns

SALICYLIC ACID 69-72-7

eyes; skin; resp tract; CNS

skin

Inhalation: cough, sore throat

Skin: may be absorbed, redness, pain

Eyes: redness, pain, blurred vision

Ingestion: nausea, vomiting, ear ringing

STEARIC ACID   57-11-4

eyes

lungs

Inhalation: cough, laboured breathing

Eyes: redness, pain

Ingestion: constipation

SULPHANILIC ACID         121-57-3

eyes; skin; resp tract; blood

skin; lungs

Inhalation: blue lips or finger nails, blue skin, cough, dizziness, headache, laboured breathing, sore throat

Skin: redness

Eyes: redness

Ingestion: blue lips or fingernails, blue skin, dizziness, headache, laboured breathing

TEREPHTHALIC ACID      100-21-0

eyes; skin

Inhalation: cough, irritant

Skin: redness, mild irritant

Eyes: redness, irritant

p-TOLUENESULPHONIC ACID     104-15-4

eyes; skin; resp tract; lungs

Inhalation: burning sensation, cough, laboured breathing

Skin: redness, pain, blisters

Eyes: redness, pain, blurred vision

Ingestion: burning sensation, sore throat

2,4,5-TRICHLOROPHENOXYACETIC ACID     93-76-5

eyes; skin; resp tract

Skin; liver; GI tract Inh; ing; con

In animals: ataxia; skin irrit, acne-like rash, liver damage

TRIMELLITIC ANHYDRIDE     552-30-7

eyes; skin; resp tract; lungs; blood

Inhalation: cough, dizziness, wheezing, chills

Skin: redness

Eyes: redness, pain

Eyes; skin; resp sys abs

Irrit eyes, skin; nose; resp sys; pulm edema, resp sens; rhinitis, asthma, cough, wheez, dysp, mal, fever, musc aches, sneez

VALERIC ACID   109-52-4

eyes; skin; resp tract; lungs; CNS

 

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