Sunday, 07 August 2011 06:37

Heterocyclic Compounds: Health Hazards

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Chemical Name

CAS-Number

ICSC Short-Term Exposure

ICSC Long-Term Exposure

ICSC Routes of Exposure and Symptoms

US NIOSH Target Organs & Routes of Entry

US NIOSH Symptoms

2-AMINOPYRIDINE          504-29-0

Inhalation: convulsions, dizziness, headache, nausea, shortness of breath, weakness, increased blood pressure, collapse

CNS; resp sys Inh; abs; ing; con

Irrit eyes, nose, throat; head, dizz, excitement; nau; high BP; resp distress; weak; convuls; stupor

3,6-DICHLOROPICOLINIC ACID     1702-17-6

eyes; resp tract

liver; kidneys

Inhalation: cough, dullness

2-MERCAPTOBENZOTHIAZOLE     149-30-4

eyes

skin

Inhalation: cough

Skin: redness

Eyes: redness, pain

2-MERCAPTOBENZOTHIAZOLE DISULPHIDE      120-78-5

eyes; skin; resp tract

skin

Inhalation: cough, sore throat

Skin: may be absorbed, redness

Eyes: redness

2-METHYLPYRIDINE        109-06-8

eyes; skin; resp tract

skin; CNS

Inhalation: burning sensation, cough, dizziness, drowsiness, headache, laboured breathing, nausea, sore throat, unconsciousness, weakness

Skin: may be absorbed, dry skin, redness, burning sensation, pain, blisters

Eyes: pain, blurred vision, severe deep burns

Ingestion: abdominal pain, burning sensation, diarrhoea, vomiting

3-METHYLPYRIDINE        108-99-6

eyes; skin; resp tract

skin; CNS

Inhalation: burning sensation, cough, dizziness, drowsiness, headache, laboured breathing, nausea, sore throat, unconsciousness, weakness

Skin: may be absorbed, dry skin, redness, burning sensation, pain, blisters

Eyes: pain, blurred vision, severe deep burns

Ingestion: abdominal pain, burning sensation, diarrhoea, vomiting

4-METHYLPYRIDINE        108-89-4

eyes; skin; resp tract

skin; CNS

Inhalation: burning sensation, cough, dizziness, drowsiness, headache, laboured breathing, nausea, sore throat, unconsciousness, weakness

Skin: may be absorbed, dry skin, redness, burning sensation, pain, blisters

Eyes: pain, blurred vision, severe deep burns

Ingestion: abdominal pain, burning sensation, diarrhoea, vomiting

1-METHYL-2-PYRROLIDONE     872-50-4

resp tract; eyes

lungs; bone marrow; lymphatic system

Inhalation: cough, laboured breathing

Skin: may be absorbed

Eyes: redness, pain, blurred vision, loss of vision; abdominal cramps, diarrhoea, laboured breathing

MORPHOLINE    110-91-8

eyes; skin; resp tract; lungs

liver; kidneys

Inhalation: Ingestion: burning sensation, cough, laboured breathing, shortness of breath, sore throat

Skin: may be absorbed, redness, skin burns, pain

Eyes: redness, pain, blurred vision

Ingestion: abdominal pain, cough, diarrhoea, vomiting

Resp sys; eyes; skin; liver; kidneys Inh; abs; ing; con

Irrit eyes, skin, nose, resp sys; vis dist; cough; in animals: liver, kidney damage

NICOTINE          54-11-5

Inhalation: abdominal pain, headache, nausea, vomiting, tremors, convulsions,

CNS; CVS; lungs; GI tract; repro sys Inh; abs; ing; con

Nau, salv, abdom pain, vomit, diarr; head, dizz, hearing, vis dist; conf, weak, inco; paroxysmal atrial fibrl; convuls, dysp; in animals: terato effects

NICOTINE TARTRATE      65-31-6

eyes; skin; CNS

Inhalation: abdominal pain, headache, nausea, vomiting, tremors, convulsions

Skin: may be absorbed

Eyes: redness, pain

PHENOTHIAZINE            92-84-2

eyes; skin; resp tract; blood; liver

skin

Inhalation: cough, sore throat

Skin: may be absorbed, redness, pain, itching, coloured yellow-brown skin

Eyes: redness, pain, blurred vision

Skin; CVS; liver; kidneys Inh; abs; ing; con

Itching, irrit, reddening skin; hepatitis, hemolytic anemia, abdom cramps, tacar; kidney damage; skin photo sens

PHENYLENEPYRENE      193-39-5

Skin: may be absorbed

PIPERIDINE       110-89-4

Inhalation: burning sensation, cough, laboured breathing

PROPYLENE IMINE         75-55-8

eyes; skin; resp tract; lungs ; CNS

skin

Inhalation: cough, dizziness, headache, laboured breathing, shortness of breath, unconsciousness

Skin: may be absorbed, redness, skin burns, itching, blisters

Eyes: redness, pain, blurred vision

Ingestion: burning sensation of the digestive tract, dizziness, headache, nausea, vomiting

Eyes; skin (in animals: nasal tumors) Inh; abs; ing; con

Eye, skin burns; (carc)

PYRIDINE          110-86-1

eyes; skin; resp tract; GI tract; CNS; CVS

skin; liver; kidneys

Inhalation: cough, dizziness, headache, nausea, shortness of breath, unconsciousness

Skin: may be absorbed, redness

Eyes: redness, pain

Ingestion: abdominal pain, diarrhoea, vomiting, weakness

Eyes; skin; CNS; liver; kidneys; GI tract Inh; abs; ing; con

Irrit eyes; head, ner, dizz, insom; nau, anor, derm; liver, kidney damage

2-PYRROLIDINONE         616-45-5

eyes

QUINOLINE        91-22-5

eyes; resp tract; CNS

liver; kidneys; retina

Inhalation: cough, laboured breathing, nausea, shortness of breath, vomiting, weakness

Skin: may be absorbed, redness, skin burns

Eyes: redness, pain, blurred vision

TETRAHYDROTHIOPHENE     110-01-0

eyes; skin; resp tract; CNS

skin

Inhalation: Burning sensation, cough, headache, sore throat

Skin: may be absorbed, dry skin, redness, burning sensation

Eyes: redness, pain, eyes

Ingestion: abdominal pain

THIOPHENE       110-02-1

eyes; skin; resp tract

Inhalation: cough, sore throat

Skin: may be absorbed

Eyes: redness, pain

 

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